How should I play [Champion A] into [Champion B] after the current patch?

I want practical lane advice here, not just a yes or no on whether the matchup is playable. Useful answers should include: - best rune page and first item - what level or wave state matters most - the fastest way to lose the lane by mistake - the safest fallback plan if the lane is rough If you have played both sides, please say what punishes the other side the hardest.